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Older biologic age linked to elevated breast cancer risk

NIH scientists use epigenetics to help predict disease development

  1. Biologic age, a DNA-based estimate of a person's age, is associated with future development of breast cancer, according to scientists.

  2. Biologic age was determined by measuring DNA methylation, a chemical modification to DNA that is part of the normal aging process.

  3. For every five years a woman's biologic age was older than her chronologic or actual age, she had a 15 percent increased risk of developing breast cancer.


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